Premarin (Conjugated Estrogens)

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PREMARIN (CONJUGATED ESTROGENS)

Premarin Information

Premarin is a member of the Conjugated Estrogens group of drugs, based on the female sex hormone estrogen. Estrogen is a hormone essential to the female physiology, on which many of the female-specific body function are based. Among the disorders that may occur when the estrogen quantity becomes insufficient, some examples are: menopause, infertility, and someBreast Cancer types, and ovary function deficiencies, degeneration of the vagina or urethra. The male human body also needs estrogen to function properly, insufficient quantities of this hormone leading to prostate cancer.

Premarin Indications

Premarin is mainly prescribed for the treatment of such disorders as:

• moderate or severe vasomotor symptoms associated with the menopause
• moderate or severe symptoms of vaginal or vulvar atrophy associated with the menopause
• hypoestrogenism due to hypogonadism, castration or primary ovarian failure
• some types of Breast Cancer
• advanced androgen-dependent carcinoma of the prostate
• prevention of postmenopausal osteoporosis – in carefully selected cases.

There are a number of other cases in which Premarin can be prescribed, so if you want to know more about why you have been prescribed this drug, consult your personal health care specialist.

Premarin Warnings

Consult with your personal health care specialist before starting to take Premarin if you are suffering of blood clotting and circulation disorders, abnormal vaginal bleedings, cancer of the breast, uterus or any type of hormone-dependent cancer, as treatment with Premarin might be dangerous in such cases. Also, special care, monitoring or altered dosages may be required for patients that are suffering or have medical history of:

This drug has been in a number of cases considered to be the main cause of malformed fetus development. Use of this drug is hazardous to an unborn child, so you should never take Premarin if you are pregnant or planning to become a mother soon. Also, Premarin may affect breast milk flow and composition, so it is advised that you should consult with your personal health care specialist before starting on this drug if you are a nursing mother.
It is also strongly advised that Premarin be prescribed at the lowest dosage and for the shortest time possible, as prolonged treatment or high dosage of this medicine can cause a number of other hormone related diseases.

Premarin Intake Guidelines

Closely follow the intake guidelines that your personal health care supervisor has given you. Should you have any trouble understanding any of the guidelines, please ask a doctor, pharmacist or nurse to help you. It is recommended that the Premarin dose should be accompanied by a glass of water, and preferably be taken on a full stomach to reduce stomach upset. Store away from heat and moisture, in a safe place, away from the reach of children.

Premarin Dosage

Consult your personal health care specialist to obtain the Premarin dosage best suited to your age and general health condition. Self-medication should never be employed when starting a treatment with this medicine. Never alter the dosage you have been given by your physician, either by modifying the drug quantity or the time interval between intakes.

Premarin Overdose

While it is very unlikely that Premarin overdose will result in fatal consequences, it is recommended that you immediately seek emergency medical care if you suspect you are suffering from an overdose with this drug and / or have unusual symptoms. The most common symptoms of Premarin overdose are nausea, vomiting and vaginal bleeding.

Premarin Missed Dose

You should set up a strict time schedule for your Premarin intakes, to prevent dose omission. However, should you happen to miss a dose, do not take a double dose to make up for the lost one, instead just return to your normal schedule.

Premarin Side Effects

One of the most serious side effects associated with Premarin treatment is the increased risk of developing cancer of the uterus, through development of endometrial hyperplasia. However, this effect can be countered by taking progestins.
Other serious side effects of Premarin use are:

• Increased risk of heart attacks or stroke


• Increased chance of developing Breast Cancer


• Increased chance of developing blood clots in the lungs or legs


• Allergic reactions (such as difficulty breathing, hives, rashes, swelling of the face, tongue or lips)


• Chest pains, shortness of breath


• Painful swollen legs


• Abnormal vaginal bleeding


• Pain, tenderness and swelling of the abdomen


• Severe headaches, blurred vision, trouble in speech, dizziness


• Jaundice


• Breast lumps

Should you happen to experience any of the above symptoms, immediately stop Premarin use and contact your personal health care specialist.
Other side effects that may occur, with less grave consequences, are:

• Nausea


• Swollen or tender breasts


• Acne or skin changes


• A decrease in the sex drive


• Headaches, migraines


• Bloating through water retention


• Depression


• Changes in the menstrual cycle

Should you experience any of these, consult your health care specialist to establish the appropriate course of action.

If you are under treatment with any of these drugs, or have recently finished treatment with any of them, please talk with your personal health care specialist as he may decide to alter your Premarin dosage and / or keep you under special monitoring for the duration of the treatment.

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Buy Premarin. It is available through our Online Pharmacy or at any Canada Pharmacy selling Online Prescriptions. In some countries PREMARIN may also be known as: Belestar, Livomarin, Estrogenon, Estroplus, Menosedan, Prem, Repogen, CES, Climatrol E, Conpremin, Estrarona, Oestrofeminal, Climopax mono, Equin, Espauz, Estrin, Dagynil, Longaplex, Cenestin, Enjuvia, Biostrogen, Climatrol E, Menostat

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What is Valtrex (VALACYCLOVIR)?

Valtrex (VALACYCLOVIR) is an antiviral drug. It slows the growth and spread of the herpes virus so that the body can fight off the infection. Valtrex (VALACYCLOVIR) will not cure herpes, but it can lessen the symptoms of the infection.Valtrex (VALACYCLOVIR) is used to treat infections caused by herpes viruses in adults and children. Illnesses caused by herpes viruses include genital herpes, cold sores, shingles, and chickenpox.Valtrex (VALACYCLOVIR) is used to treat cold sores in children who are at least 12 years old, and to treat chickenpox in children who are at least 2 years old.Valtrex (VALACYCLOVIR) may also be used for other purposes not listed in this medication guide.

Important information about Valtrex (VALACYCLOVIR)

Before taking Valtrex (VALACYCLOVIR), tell your doctor if you have HIV/AIDS, a weak immune system, kidney disease (or if you are on dialysis), or if you have had a kidney or bone marrow transplant. Valtrex (VALACYCLOVIR) can be harmful to the kidneys, and these effects are increased when it is used together with other medicines that can harm the kidneys. Tell your doctor about all other medications you are using. You may need dose adjustments or special tests when taking certain medications together with Valtrex (VALACYCLOVIR).Treatment with Valtrex (VALACYCLOVIR) should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).Herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes, it is very important to prevent herpes lesions during your pregnancy so that you do not have a genital lesion when your baby is born. Valtrex (VALACYCLOVIR) will not prevent the spread of genital herpes. Herpes infections are contagious and you can infect other people even while you are taking with Valtrex (VALACYCLOVIR).Stop taking Valtrex (VALACYCLOVIR) and call your doctor right away if you have any signs of a serious side effect that can harm red blood cells, such as: fever, easy bruising or bleeding, red spots on the skin (not related to herpes or chickenpox), bloody diarrhea, vomiting, pale or yellowed skin, weakness, fainting, or urinating less than usual or not at all.Do not give Valtrex (VALACYCLOVIR) to a child unless it has been prescribed by a doctor.

Before taking Valtrex (VALACYCLOVIR)

Do not take this medicine if you are allergic to valacyclovir or acyclovir (Zovirax). If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking Valtrex (VALACYCLOVIR), tell your doctor if you have:HIV/AIDS, or other conditions that can weaken the immune system;kidney disease (or if you are on dialysis); orif you have had a kidney or bone marrow transplant.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. However, herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes, it is very important to prevent herpes lesions during your pregnancy so that you do not have a genital lesion when your baby is born. Valtrex (VALACYCLOVIR) passes into breast milk and may harm a nursing infant. Do not take this medication without telling your doctor if you are breast-feeding a baby. Do not give Valtrex (VALACYCLOVIR) to a child unless it has been prescribed by a doctor. Older adults may be more likely to have harmful side effects while taking Valtrex (VALACYCLOVIR). Talk to your doctor about your specific risk.

How should I take Valtrex (VALACYCLOVIR)?

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Valtrex (VALACYCLOVIR) will not treat a viral infection such as the common cold or flu. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.Store Valtrex (VALACYCLOVIR) tablets at room temperature away from moisture and heat.

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Store Valtrex (VALACYCLOVIR) liquid in a refrigerator. Do not freeze. Throw away any unused Valtrex (VALACYCLOVIR) that is older than 28 days. 

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include urinating less than usual or not at all.

What should I avoid while taking Valtrex (VALACYCLOVIR)?
Valtrex (VALACYCLOVIR) will not prevent the spread of genital herpes. Herpes infections are contagious and you can infect other people even while you are taking with Valtrex (VALACYCLOVIR).Avoid sexual intercourse or use a latex condom to prevent spreading the virus to others. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Side effects of Valtrex (VALACYCLOVIR):

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Valtrex (VALACYCLOVIR) and call your doctor right away if you have any of the following signs of a serious side effect that can harm red blood cells:fever, easy bruising or bleeding;red spots on the skin (not related to herpes or chickenpox);bloody diarrhea, vomiting;pale or yellowed skin;weakness or fainting; orurinating less than usual or not at all.
Call your doctor at once if you have any of these other serious side effects: pain in your lower back;drowsiness, mood changes, increased thirst, loss of appetite, nausea and vomiting;swelling, weight gain, feeling short of breath;confusion, agitation, aggression, hallucinations, trouble concentrating;feeling shaky or unsteady;problems with speech or vision; orseizure (convulsions).

What other drugs will affect Valtrex (VALACYCLOVIR)?

kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled);antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); orcancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid).This list is not complete and there may be other drugs that can interact with Valtrex (VALACYCLOVIR). Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

SIDE EFFECTS OF Valtrex (VALACYCLOVIR)

For the Consumer

Applies to valacyclovir: oral tablet

Along with its needed effects, valacyclovir (the active ingredient contained in Valtrex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking valacyclovir:

Rare
- Black, tarry stools
- chest pain
- chills
- cough
- decreased frequency or output of urine
- fever
- flu-like symptoms
- headache
- lower back or side pain
- reduced mental alertness
- shortness of breath
- yellow eyes or skin

Incidence not known
- Actions that are out of control
- agitation
- anxiety
- back, leg, or stomach pains
- bleeding gums
- blood in urine or stools
- blurred vision
- change in consciousness
- change in mental status
- changes in behavior, especially in interactions with other people
- changes in patterns and rhythms of speech
- dark or bloody urine
- difficult or labored breathing
- difficulty speaking
- difficulty swallowing
- dizziness
- drowsiness
- dry mouth
- fast, pounding, or irregular heartbeat or pulse
- feeling that others are watching you or controlling your behavior
- feeling that others can hear your thoughts
- feeling, seeing, or hearing things that are not there
- general tiredness and weakness
- hyperventilation
- increased thirst
- itching
- lightheadedness when getting up from a lying or sitting position
- light-colored stools
- loss of consciousness
- mood or mental changes
- nausea and vomiting
- nervousness
- pale color of skin
- pinpoint red spots on the skin
- pounding in the ears
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- restlessness
- seeing, hearing, or feeling things that are not there
- seizures
- severe mood or mental changes
- shakiness and unsteady walk
- shakiness in the legs, arms, hands, or feet
- skin rash
- slurred speech
- sores, ulcers, or white spots on the lips or in the mouth

Some side effects of valacyclovir may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
- Body aches or pain
- cramps
- difficulty in moving
- ear congestion
- heavy bleeding
- loss of voice
- muscle aches
- muscle pain or stiffness
- nasal congestion
- pain
- pain in joints
- sneezing
- sore throat
- stuffy or runny nose

Less common
- Constipation
- diarrhea

Incidence not known
- Blistering, peeling, or loosening of the skin
- hair loss or thinning of the hair
- hives or welts
- increased sensitivity of skin to sunlight
- red, irritated eyes
- redness or other discoloration of the skin
- severe sunburn

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